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CCBAR Newsletter - April, 2006

CCBAR News

• Registration for 2006 Chicago Biomarker Workshop continues. Please contact Alicia Frasier <frasier-alicia@norc.org> for details.

 

• 2005 Chicago Biomarker Workshop Proceedings are now available online

News From the Nature Journals, Science, and PNAS

• Stem cell aging: what bleach can teach
Intracellular oxidants may contribute to overall lifespan, in part by affecting stem cells. The connection between oxidants and aging now gains strength in a study of hematopoietic stem cells, which respond to oxidants by activating a pathway leading to stem cell exhaustion.  

• CD30 is a survival factor and a biomarker for transformed human pluripotent s...

 

• [PERSPECTIVES] BIOMEDICINE: Lowering LDL--Not Only How Low, But How Long?
People with a mutation in a proteolytic enzyme are at a substantially lower risk for coronary heart disease because of their lifelong reduction of plasma low-density lipoprotein. Authors: Michael S. Brown, Joseph L. Goldstein

 

• [Medical_Sciences] Delayed testicular aging in pituitary adenylate cyclase-ac...
Age-related decline in male sex hormones is a direct consequence of testicular aging. These changes in the hormonal complement cause...

• [Neuroscience] Between-subject transfer of emotional information evokes speci...
Emotional states displayed by an animal or a human can seriously affect behavior of their conspecifics. The amygdala plays a...

• [Anthropology] Cortisol levels and very early pregnancy loss in humans
Maternal stress is commonly cited as an important risk factor for spontaneous abortion. For humans, however, there is little physiological...

Biomarkers and Aging in the News Media

• Severe calorie restriction reduces aging-related cell damage
Longevity researchers say they've shown for the first time that following a strict low-calorie diet can decrease DNA damage linked ...

• When it comes to the mind, use it or lose it
New research suggest that lifestyle choices can be as important as genetics in determining how our brains age and that simple changes can help combat, and sometimes reverse, the memory loss that comes with getting older.

• 7 Ways to Help Curb Cancer Death Risk
A new report from the American Cancer Society estimates that at least half of all cancer deaths "could in principle be avoided" with some lifestyle changes.

• Ovary Removal May Up Dementia Risk
Women who undergo ovary removal before menopause may have an increased risk of dementia, a Mayo Clinic study suggests.

• Aspirin equally heart-protective in men and women
"Women are clearly benefiting from taking aspirin and should continue to take it to improve their cardiovascular health," Dr. Diane M. Becker states in a Johns Hopkins press release. "Aspirin has been proven by all previous studies to lower the risk of stroke and, as our latest findings show, it also reduces platelet aggregation that can lead to potentially fatal clots in blood vessels."

• HDL cholesterol level predicts heart events
NEW YORK (Reuters Health) - Levels of HDL cholesterol -- the good cholesterol -- can be used to predict major adverse coronary events, independent of other heart and circulatory risk factors, according to a report published this month.

• Breast Size Studied As Cancer Risk
Few women have perfectly symmetrical breasts, but larger differences in size, according to a study in the U.K., might be a risk factor for breast cancer. The American Cancer Society calls the findings "interesting" but "very preliminary."

• X Chromosomes Key To Sex Differences In Health
Females have two X chromosomes and males only have one -- and this simple fact, along with the occurrence of what geneticists call mosaicism, may not only explain why women are less susceptible than men to certain genetic diseases, but also may account for the female prevalence in the incidence of other conditions and even sex differences in behavior, according to a special communication in the March 22/29 issue of JAMA, a theme issue on women's health.


More up-to-date news is available at the CCBAR website

 

 

 NIH Press Releases

NIH Announcements

Events

2006 Chicago Biomarker Workshop, Chicago, June 8-9, 2006

C2S Summer Biomarker Institute, Chicago, June 19-21, 2006
Application deadline: April 7, 2006


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This Newsletter  is supported by a grant from the National Institute on Aging, National Institutes of Health (Grant No. 5 P30 AG012857)


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