Editors:
Natalia Gavrilova and Stacy Tessler Lindau
Life
and death during the Great Depression [Social_Sciences]
Recent events highlight the importance of examining the impact of
economic downturns on population health. The Great Depression of the...
From
the Cover: Long-term risk preference and suboptimal decision making
foll...
Individuals who abused alcohol at an early age show decision-making
impairments. However, the question of whether maladaptive choice
constitutes a...
Trends
in Down's syndrome live births and antenatal diagnoses in England and
...
Objectives To describe trends in the numbers of Down’s
syndrome live births and antenatal diagnoses in England and Wales from
1989 to 2008.
Design and setting The National Down Syndrome Cytogenetic
Register holds details of 26488 antenatal and postnatal diagnoses of
Down’s syndrome made ...
ORIGINAL
CONTRIBUTION: Omega-3 Augmentation of Sertraline in Treatment of Dep...
Context Studies of depressed psychiatric patients
have shown
that antidepressant efficacy can be increased by augmentation with
omega-3 fatty acids.
Objective To determine whether omega-3 improves the
response
to sertraline in patients with major depression and coronary heart
disease (CH...
ORIGINAL
CONTRIBUTION: Cardiovascular Diseases and Risk of Hip Fracture
Context Recent studies indicate common etiologies for
cardiovascular disease (CVD) and osteoporotic fractures.
Objectives To examine the relation between CVD and risk of
hip fracture in twins and evaluate the relative importance of genetics
and lifestyle factors in this association.
• Three
U.S. Scientists' Genetic Work Earns Nobel Prize for Medicine
Three American
scientists shared a Nobel Prize on Monday for
deciphering how cells protect their genes as they divide repeatedly
throughout an organism's life, a crucial discovery with far-reaching
implications for aging's effects, as well as cancer and other diseases.
• U.S.
Kids May Need More Vitamin D
Millions of
children in the U.S. may not have enough vitamin D, and
African-American and Hispanic kids are especially at risk, a new study
suggests.
• Why
experts say younger, smarter wives make for a long marriage
The secret to a
happy marriage for men is choosing a wife who is smarter and at least
five years younger than you, say experts.
• Fat
liver, not belly, may be best indicator of health problems
For years,
scientists have warned people that having an apple-shaped figure or a
beer belly is a health risk.
• Consumer
Reports Insights: To thrive longer, get stronger
Which is more
important for healthy aging: exercises that work the
heart and lungs, or muscle- pumping strength training? Both are
valuable, of course, but many experts now say strength training may be
the key to preventing disability as you age. Declining muscle mass not
only undermines your phy...
• With
aging, it's like mother, like daughter
There may be
some truth to the saying that all women will eventually
turn into their mothers, with a U.S. study finding daughters age and
wrinkle like their mothers.
• Decline
in Fitness Accelerates After Age 45
Fitness levels
decline with age and accelerates after age 45 in men and
women, a new study says, but staying at a healthy weight and engaging
in regular physical activity can help determine fitness levels, too.
• Nothing
to Fear From the Big Bald Wolf
Elk have little
to fear from an aging predator [Read more]
• Heart
Attacks on the Rise in Women
Two new studies
show the number of heart attacks among middle-aged
women is rising while falling among men, but the risk of death after a
heart attack is improving more for women than men.
• Are
you at risk for sudden death?
Heart attacks
aren't just for older, overweight men with high
cholesterol and high blood pressure. Even if you work out and eat
healthy, you could still be at risk.
• Maternal
High-Fat Diet Has Serious Implications For Brain Development Of Offs...
Feeding high-fat
food to pregnant mice can affect their pups' brain development in ways
that may cause them to be more vulnerable to obesity and to engage in
addictive-like behaviors in adulthood, a new study has found.
• Losing
While Cruising To The Store: Obesity Linked To Fewer Neighborhood
Food...
Contrary to what
you might believe, living near a variety of restaurants, convenience
stores, supermarkets and even fast food outlets actually lowers your
risk for obesity, according to a new study. Surprisingly, people who
live more than a half mile away from any food outlets are the ones who
tend to be fatter.
• Scientists
Discover Gene That 'Cancer-proofs' Naked Mole Rat's Cells
Despite a
30-year lifespan that gives ample time for cells to grow cancerous, a
small rodent species called a naked mole rat has never been found with
tumors of any kind -- and now biologists think they know why.
• Marker
May Predict Multiple Sclerosis Severity
A newly
identified biomarker may be linked to the severity of multiple
sclerosis and may one day help with diagnosis and treatment of the
often frustrating and unpredictable disease.
• VItal
Signs: Babies Born to Childhood Cancer Survivors Do Well
Newborns of
cancer survivors did not face an increased risk of birth defects or
death.
• Protect
your breasts ? get your heart pumping
Exercise
is known to help reduce a woman?s risk of breast cancer.
But how much and what kind is best? Recent research helps women
maximize their efforts.
• Vital
Signs: Nutrition: Lower Depression Risk Linked to Mediterranean Diet
A Mediterranean
may protect not just the heart, but mental health as well, a new study
finds.
• Gene
Tweak May Keep Hearts Younger
A certain form
of the P13K gene could be a key to keeping the heart
young and preventing age-related heart failure, Japanese researchers
report.
• Gene
Linked to Longer, Skinnier Life
Scientists have
discovered a gene called S6K1 that may affect longevity and leanness.
• Vitamin
D May Help Prevent Falls
Taking vitamin D
supplements, at a dose of 700-1000 international units
per day, may make falling 19% less likely for people age 65 and older.
• Signs
Of Macular Degeneration May Predict Heart Disease
A large study
found strong evidence that older people who have
age-related macular degeneration (AMD) are at increased risk for
coronary heart disease (CHD), although not for stroke. This result adds
to mounting evidence that AMD and cardiovascular disease may share some
risk factors--smoking, high blood pressure, inflammatory indicators
such as C-reactive protein, genetic variants such as complement factor
H--and disease mechanisms.
• Women's
Weight Tied to Healthy Aging
For women, the
odds of being healthy at age 70 are best for those who
don't gain a lot of weight between ages 18 and 50 and who aren't obese
at 50, a new study shows.
NIH
Press Releases
Study
Conclusively Ties Rare Disease Gene to Parkinson's
An international
team led by a National Institutes of Health researcher
has found that carriers of a rare, genetic condition called Gaucher
disease face a risk of developing Parkinson's disease more than five
times greater than the general public. The findings were published
today in the New England Journal of Medicine.
NHGRI
Launches Improved Online Talking Glossary of Genetic Terms
The National
Human Genome Research Institute (NHGRI), part of the
National Institutes of Health, today launched the next generation of
its online Talking Glossary of Genetic Terms. The glossary contains
several new features, including more than 100 colorful illustrations
and more than two dozen 3-D animations that allow the user to dive in
and see genetic concepts in action at the cellular level.
NIH Awards
New Grants to Build Capacity in Informatics in Global Health
The Fogarty
International Center, part of the National Institutes of
Health, today announced it will award more than $9.23 million to eight
global health informatics programs over the next five years. Fogarty's
Informatics Training for Global Health program is intended to increase
informatics expertise in low- and middle-income countries by training
scientists to design information systems and apply computer-supported
management and analysis to biomedical research. Medicine and biomedical
research are knowledge-based fields that depend upon the sharing of
information. Informatics, the science of handling large volumes of
information, can help link physicians and researchers around the world
so that they can share knowledge ranging from the best care of patients
to issues in collaborative research.
Investment
in Parkinson's Disease Data Bank Yields Potential Therapy
Individuals with
Parkinson's disease who have higher levels of a
metabolite called urate in their blood and in cerebrospinal fluid (CSF)
have a slower rate of disease progression, according to a study funded
by the National Institutes of Health.
NIH Awards
Grants to Examine Factors Influencing Women's Careers in Science
The National
Institutes of Health announced today that it will fund 14
grants focusing on factors that influence the careers of women in
biomedical and behavioral science and engineering. The grants are
estimated to total $16.8 million over four years.
NHLBI to
Convene Symposium on Cardiovascular Regenerative Medicine
With
advancements in the field of stem cell research accelerating, the
National Heart, Lung, and Blood Institute (NHLBI) of the National
Institutes of Health (NIH) will hold its third Symposium on
Cardiovascular Regenerative Medicine to review the latest findings in
the field and examine future directions. The symposium will include a
discussion on ways to move promising findings in the laboratory into
clinical trials, in hopes of speeding stem cell-related treatments to
patients.
NIH
Grantees Win 2009 Nobel Prize in Physiology or Medicine for Telomere
Rese...
The 2009 Nobel
Prize in physiology or medicine is shared by three
grantees of the National Institutes of Health (NIH): Elizabeth H.
Blackburn, Ph.D, of University of California, San Francisco; Carol W.
Greider, Ph.D, of Johns Hopkins University School of Medicine; and Jack
W. Szostak, Ph.D, of Massachusetts General Hospital, Harvard Medical
School and Howard Hughes Medical Institute. The three researchers,
supported by NIH funding for decades, are honored for discovering how
chromosomes are protected against degradation by telomeres through the
enzyme telomerase. Their discoveries added a new dimension to the
scientific community's understanding of the cell, shed light on disease
mechanisms, and introduced new directions for the development of
potential new therapies.
NIH
Announcements
Restructured
Application Forms and Instructions for Submissions for FY2011 Fu...
Notice from the
NIH Guide for Grants and Contracts
Nathan
Shock Centers Of Excellence in Basic Biology of Aging (P30)
RFA-AG-10-009, Expiration Date: December 12, 2009
Secondary
Analyses of Existing Data Sets and Stored Biospecimens to Address
Clinical Aging Research Questions (R01)
PA-09-265, Expiration Date: January 8, 2013
Summer
Research Training in Aging for Medical Students (T35)
RFA-AG-10-007, Expiration Date: December 4, 2009
NIA
Intervention Testing Program Solicits Proposals for Compounds to Test
for Anti-Aging Activity in Mice
NOT-AG-09-007 Receipt for Proposals: December 18, 2009
Effects
of Gene-Social Environment Interplay on Health and Behavior in Later
Life (R01)
RFA-AG-10-006 Expiration date: 2009/11/10
Healthy
Aging through Behavioral Economic Analyses of Situations (R01)
RFA-AG-10-008 Expiration date: 2009/11/03
Exploratory
Innovations in Biomedical Computational Science and Technology (R21)
PAR-09-219 Expiration date: 2012/09/08
The
Human Connectome Project (U54)
RFA-MH-10-020 Expiration date: 2009/11/25
Development
and Validation of Disease Biomarkers (R01)
(PA-09-204)
Identification and Characterization of
Sensitive Periods for Neurodevelopment...
Request for Applications from the NIH Guide for Grants and Contracts
Events
NIH videocasts:
Conferences:
Gerontological
Society of America Annual meeting will be held
November 18-22, 2009 in Hilton and Marriott Marquis,
This Newsletter is supported
by a grant from the National Institute on Aging, National Institutes of
Health (Grant No. 5 P30 AG012857)
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